6 Purple glove syndrome developed in 6% (9/152) of patients who received IV phenytoin.() 6 Purple glove syndrome developed in 6% (9/152) of patients who received IV phenytoin. Although utilizing administration precautions may reduce the risk of PGS from the administration of IV phenytoin, the syndrome still may occur despite careful technique (Snelson & Dieckman, 2000).() Although utilizing administration precautions may reduce the risk of PGS from the administration of IV phenytoin, the syndrome still may occur despite careful technique (Snelson & Dieckman, 2000).
Anticonvulsant hypersensitivity syndrome has been linked to a defect in the enzyme epoxide hydrolase.
purple glove syndrome Purple glove syndrome (PGS) is a rare complication of intravenous phenytoin use that typically presents with pain, edema, and discoloration at the injection site that spreads to the distal limb.() Purple glove syndrome (PGS) is a rare complication of intravenous phenytoin use that typically presents with pain, edema, and discoloration at the injection site that spreads to the distal limb.
H. Oda Purple Glove Syndrome Caused by Oral Administration of Phenytoin J Child Neurol, November 1, 2000; 15(11): 762 - 762.
W. R. J. R. R. Browne Incidence and clinical consequence of the purple glove syndrome in patients receiving intravenous phenytoin Neurology, October 22, 1999; 53(7): 1611 - 1611.
R. N Mehta, and E. Mohler III Purple glove syndrome following intravenous phenytoin administration Vascular Medicine, February 1, 2007; 12(1): 29 - 31.
Find out more about this strange condition called Purple Glove Syndrome at the link provided.
Purple glove syndrome following intravenous phenytoin administration — Chokshi et al. Incidence and clinical consequence of the purple glove syndrome in patients receiving intravenous phenytoin — O’Brien et al. Purple Glove Syndrome
